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Nov 12, 2019

A Phase Ib/II clinical trial of DDFPe as a radiosenzitizer in glioblastoma

Although small, this trial shows that DDFPe used as a radiosensitizer appears to be safe and may provide some survival benefit.

Apr 16, 2016

TOLD MRI validation of reversal of tumor hypoxia in glioblastoma with a novel oxygen therapeutic

MRI scans indicated that oxygen breathing with DDFPe administration improved tumor oxygenation.

Mar 1, 2016

Reversal of Tumor hypoxia following intravenous delivery of DDFPe

DDFPe results in a significant increase in intra-tumoral oxygen tension for up to 45 minutes in our pancreatic xenograft model in mice.

Nov 10, 2015

Dynamic Oxygenation Measurements Using a Phosphorescent Coating Window Chamber Model

Intravenous injection of DDFPe in mice with tumors increases tumor oxygen levels.

Feb 1, 2015

Radiosensitization of Hs-766T Pancreatic Tumor Xenografts in Mice Dosed with DDFPe

DDFPe administration in mice with pancreatic tumor xenografts resulted in increased tumor oxygen tension lasting up to two hours.

Jul 1, 2002

Radiosensitization of hypoxic tumor cells by DDFPe

DDFP plus carbogen appears to completely reverse the hypoxic cell radioresistance in this rat tumor model.

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