NuvOx Pharma is a biotechnology company based in Tucson, Arizona with a novel patent portfolio allowing it to develop an innovative platform of oxygen therapeutics to treat life-threatening diseases where hypoxia plays a role.
NuvOx's formulations are based on dodecafluoropentane emulsion (DDFPe). The emulsions are injected intravenously, flow through the lungs and pick up oxygen, then flow through the blood and offload the oxygen to hypoxic tissue. Pre-clinical data has shown efficacy in several indications including hypoxic solid tumors, stroke, sickle cell crisis, hemorrhagic shock, traumatic brain injury, and myocardial infarction. The company is in the clinical stage for oncology, stroke, and sickle cell crisis.
Painting by Diane Fairfield