Jul 1, 2002Radiosensitization of hypoxic tumor cells by DDFPeDDFP plus carbogen appears to completely reverse the hypoxic cell radioresistance in this rat tumor model.
Sep 10, 2001DDFPe Provides Vital Oxygenation In Hemoglobin Depleted Pigs during Air BreathingUS Army Studies concluding that DDFPe holds promise in combat casualty care, even when oxygen is not readily available.
Apr 27, 2001Human pharmacokinetics of a DDFPe with gas chromatographyIn this human PK study, DDFPe was given to 24 volunteers. DDFPe blood concentration decreases quickly. The drug is exhaled unmetabolized.
Nov 11, 2000DDFPe for treatment of hypoxemia due to an experimental pulmonary shuntPigs had airways blocked and were given 100% O2 to breathe. DDFPe infusions increase arterial oxygen tensions within minutes.